Tanshinol borneol ester
Tanshinol borneol ester, an angiogenesis stimulator, promoted multiple key steps of angiogenesis through Akt and MAPK signalling pathways. Tanshinol borneol ester has anti-ischemic and anti-atherosclerosis activities.
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- CAS No.: 1623012-10-1
- 화학식: C19H26O5
- 분자량:334.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All AMPK Isoforms
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Biological Activity
제품 설명
IC50 & Target
[1]|
Akt |
AMPK |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6 mouse Matrigel plug model[1]
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Dosage:0.2, 1, and 5 mg/kg
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Administration:IP; daily; 8 days
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Result:Produced significant increases in blood content compared with vehicle control, while no significant increase in haemoglobin content at the highest dose (25 mg/kg).
Significantly increased microvessel formation.
Chemical Information
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CAS No. 1623012-10-1
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분자량 334.41
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화학식 C19H26O5
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SMILES
C[C@](C1(C)C)(CC[C@]1([H])C2)[C@H]2OC([C@H](O)CC(C=C3)=CC(O)=C3O)=O
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Sha Liao, et al. Tanshinol borneol ester, a novel synthetic small molecule angiogenesis stimulator inspired by botanical formulations for angina pectoris. [Content Brief]
[2]. Pu Jia, et al. The anti-atherosclerotic effect of tanshinol borneol ester using fecal metabolomics based on liquid chromatography-mass spectrometry. Analyst. 2016 Feb 7;141(3):1112-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)