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Cat. No.: HY-180880

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TFAP2β modulator-1

TFAP2β modulator-1 (compound A6) is a potent TFAP2β modulator that promotes TFAP2β condensation by inducing conformational changes in the intrinsically disordered region. TFAP2β modulator-1 promotes TFAP2β condensation, induces apoptosis, and exhibits anti-tumor functions in esophageal squamous cell carcinoma (ESCC) cells, mouse models, and organoids. TFAP2β modulator-1 can be used for ESCC research.

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CAS No.: 668435-69-6
화학식: C₁₇H₁₁Cl₂N₃O
분자량:344.19

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

TFAP2β modulator-1 Chemical Structure

CAS No.: 668435-69-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

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Chemical Information

CAS No. 668435-69-6
분자량 344.19
화학식 C₁₇H₁₁Cl₂N₃O
SMILES

ClC(C1=C(N(C2=O)C)C=CC(Cl)=C1)=C2C3=NC4=CC=CC=C4N3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Deng Z, et al. Targeting TFAP2β condensation suppresses the development of esophageal squamous cell carcinoma. Cell. 2025 Dec 16:S0092-8674(25)01315-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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