Tipifarnib (Standard)
Tipifarnib (Standard) is the analytical standard of Tipifarnib (HY-10502). This product is intended for research and analytical applications. Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC50 of 0.86 nM. Antineoplastic activity and antiparasitic activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 95%
- CAS No.: 192185-72-1
- 화학식: C27H22Cl2N4O
- 분자량:489.40
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-10502
TipifarnibFTase Inhibitor -
HY-15136
LonafarnibFarnesyltransferase Inhibitor -
HY-15872A
FTI-277 hydrochlorideFTase Inhibitor -
HY-50876
DaporinadNMPRT Inhibitor -
HY-10038
A 922500DGAT-1 Inhibitor -
HY-16273A
L-778123 hydrochlorideFarnesyl Transferase Inhibitor -
HY-17406
TolcaponeCOMT Inhibitor -
HY-N6796
Manumycin AAntibiotic, TrxR-1 Inhibitor -
HY-15879
LB42708Farnesyltransferase Inhibitor -
HY-108467
GGsTopγ GGT Inhibitor -
HY-16373
CP-609754Farnesyltransferase Inhibitor -
HY-16273
L-778123FPTase/GGPTase-I Iinhibitor
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 192185-72-1
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분자량 489.40
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화학식 C27H22Cl2N4O
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SMILES
O=C1N(C2=C(C(C3=CC=CC(Cl)=C3)=C1)C=C(C=C2)[C@@](N)(C4=CN=CN4C)C5=CC=C(C=C5)Cl)C
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Synonyms
IND 58359 (Standard); R115777 (Standard)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Devendra S Puntambekar, et al. Inhibition of farnesyltransferase: a rational approach to treat cancer? J Enzyme Inhib Med Chem. 2007 Apr;22(2):127-40. [Content Brief]
[2]. End DW, et al. Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro. Cancer Res. 2001 Jan 1;61(1):131-7 [Content Brief]
[3]. Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tipifarnib (Standard) Related Classifications
HY-10502R Related Classifications
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