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Tisotumab

(Synonyms: Anti-Human F3 Recombinant Antibody)
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Based on 1 publication(s) in Google Scholar

Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody and ADC antibody. Tisotumab targets tissue factor (TF). Tisotumab can be used to synthesize antibody-drug conjugates (ADCs) targeting tissue factor (TF), Tisotumab vedotin (HY-152963). Tisotumab can be used for the research of solid tumors.

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  • Experimental Validation Results for Tisotumab
  • Experimental Validation Results for Tisotumab
  • Experimental Validation Results for Tisotumab
  • Tisotumab Chemical Structure
    Tisotumab Chemical Structure
CAS No.: 1418628-81-5
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Tissue Factor Protein, Human can bind Tisotumab. The EC50 for this effect is 10.79 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 A431 cells labeling TF with Tisotumab (HY-P99271, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Tisotumab Chemical Structure
    1/16
  • Tisotumab
  • Immobilized Tissue Factor Protein, Human can bind Tisotumab. The EC50 for this effect is 10.79 ng/mL.
  • Flow cytometric analysis of 1X106 A431 cells labeling TF with Tisotumab (HY-P99271, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).