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Cat. No.: HY-120172

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WAY-126299A

WAY-126299A is an orally active dual-acting 5-1ipoxygenase inhibitor (IC₅₀: 12.2 μM) and leukotriene D4 antagonist (pK_B: 6.4). WAY-126299A inhibits antigen-induced leukotriene-dependent bronchoconstriction. WAY-126299A can be used for research of asthma.

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CAS No.: 169626-43-1
화학식: C₂₂H₁₉N₂NaO₃S
분자량:414.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

WAY-126299A Chemical Structure

CAS No.: 169626-43-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

5-Lipoxygenase

12.2 μM (IC₅₀)

All Lipoxygenase Isoforms :

All Leukotriene Receptor Isoforms :

Chemical Information

CAS No. 169626-43-1
분자량 414.45
화학식 C₂₂H₁₉N₂NaO₃S
SMILES

O=C([C@H](C1=CC=C2C=C(C=CC2=C1)OCC3=NC4=CC=CC=C4S3)C)N(C)O[Na]
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Howell RE, et al. Pulmonary pharmacology of WAY-126299A: a dual-acting 5-lipoxygenase inhibitor and leukotriene D4 antagonist. Inflamm Res. 1995 Aug;44 Suppl 2:S170-1. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
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순도&문서
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WAY-126299A

All Lipoxygenase Isoforms

All Leukotriene Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

WAY-126299A Related Classifications

HY-120172 Related Classifications