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Cat. No.: HY-120167

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YM-44778

YM-44778 is a neurokinin receptor antagonist. The _pK_i values for NK1, NK2 and NK3 are 8.08, 8.55 and 8.24, respectively. YM-44778 inhibits the increase of bladder pressure induced by substance [Sar9,Met(O2)11] -P (HY-P1012) in anestheticized rats.

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CAS No.: 173941-74-7
화학식: C₃₄H₃₉Cl₂N₃O₅
분자량:640.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

YM-44778 Chemical Structure

CAS No.: 173941-74-7

사이즈

가격

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수량

Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All Neurokinin Receptor Isoforms :

Chemical Information

CAS No. 173941-74-7
분자량 640.60
화학식 C₃₄H₃₉Cl₂N₃O₅
SMILES

O=C(C1=CC(OC)=C(C(OC)=C1)OC)N(C)CC(CCN2CCC3(NC(CC4=C3C=CC=C4)=O)CC2)C5=CC=C(C(Cl)=C5)Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Choppin A, et al. Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model. Pharmacology. 2002;65(2):96-102. [Content Brief]

Calculators

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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