YOK24
YOK24 is an orally active MetAP2 inhibitor and anti-amoebic agent. YOK24 binds covalently to MetAP2 and inhibits its peptidase activity, where MetAP2 is a protein essential for the proliferation of *Entamoeba histolytica*. YOK24 can be used in the research of amoebiasis.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3075693-57-8
- 화학식: C17H24O6
- 분자량:324.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
YOK24 potently inhibits Entamoeba histolytica growth with an ED50 of 15.5 nM and maintains this activity after incubation with hamster liver microsomes[1].
YOK24 (10 μM) shows no cytotoxicity toward Huh-7 human hepatocellular carcinoma cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3075693-57-8
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분자량 324.37
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화학식 C17H24O6
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SMILES
CC(O[C@@H]1C(CC[C@]2(CO2)[C@@]1(O)[C@]3(O[C@@H]3C/C=C(C)\C)C)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YOK24 Related Classifications
HY-181643 Related Classifications
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