KRAS G12D-IN-35
KRAS G12D-IN-35 (example 7) is a potent and orally active KRAS G12D inhibitor. KRAS G12D-IN-35 suppresses p-ERK in AGS cells and potently inhibits the proliferation of various KRAS G12D-mutant cancer cell lines. KRAS G12D-IN-35 inhibits tumor growth in HPAC and GP2D mouse models. KRAS G12D-IN-35 can be used for cancer research, such as pancreatic and colorectal cancer.
For research use only. We do not sell to patients.
- Formula: C38H33D3F4N6O3
- Molecular Weight:703.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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KRas G12D |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Molecular Weight 703.74
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Formula C38H33D3F4N6O3
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SMILES
C#CC1=C(F)C=CC2=CC(O)=CC(C3=NC4=C5C(N6C[C@H]7CC[C@H](N7)[C@H]6[C@H](C([2H])([2H])[2H])O4)=NC(OCC8(CN9CC/C(CC9)=C(F)\F)CC8)=NC5=C3F)=C21
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRAS G12D-IN-35 Related Classifications
HY-180885S Related Classifications
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