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Art. -Nr.: HY-125374S

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Larotaxel-d₉

Name: Larotaxel-d9
Brand: MedChemExpress
SKU: HY-125374S
Availability: PreOrder

(Synonyms: XRP9881-d₉)

Larotaxel-d₉ (XRP9881-d₉) is the deuterium labeled Larotaxel (HY-125374). Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₄₅H₄₄D₉NO₁₄
Molecular Weight:840.96

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Larotaxel-d₉ Chemical Structure

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Biologische Aktivität
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Chemical Information
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Bioz

Biologische Aktivität

Beschreibung

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 156294-36-9
Molecular Weight 840.96
Formel C₄₅H₄₄D₉NO₁₄
SMILES

O=C([C@]1([H])OC(C)=O)[C@@]23[C@@]([C@@H]([C@@]4(O)C(C)(C)C1=C([C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=O)C4)C)OC(C6=CC=CC=C6)=O)([H])[C@]7([C@@](OC7)([H])C[C@@H]2C3)OC(C)=O
Synonyms

XRP9881-d₉
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.