Linsidomine hydrochloride (Synonyms: SIN-1 chloride)

Cat. No.: HY-101200 Purity: 99.27%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion.

For research use only. We do not sell to patients.

Linsidomine hydrochloride Chemical Structure

CAS No. : 16142-27-1

Size	Price	Stock	Quantity
5 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 130	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Linsidomine hydrochloride:

3-Morpholinosydnonimine Get quote

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
Customer Review

Description

SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation^[1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion^[2].

Molecular Weight

206.63

Formula

C₆H₁₁ClN₄O₂

CAS No.

16142-27-1

Appearance

Solid

Color

White to off-white

SMILES

NC1=C[N+](N2CCOCC2)=NO1.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (241.98 mM; Need ultrasonic)

DMSO : 25 mg/mL (120.99 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8396 mL	24.1978 mL	48.3957 mL
5 mM	0.9679 mL	4.8396 mL	9.6791 mL
10 mM	0.4840 mL	2.4198 mL	4.8396 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.27%

Select Batch:

Data Sheet (272 KB) SDS (392 KB)

COA (248 KB) HNMR (246 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	4.8396 mL	24.1978 mL	48.3957 mL	120.9892 mL
	5 mM	0.9679 mL	4.8396 mL	9.6791 mL	24.1978 mL
	10 mM	0.4840 mL	2.4198 mL	4.8396 mL	12.0989 mL
	15 mM	0.3226 mL	1.6132 mL	3.2264 mL	8.0659 mL
	20 mM	0.2420 mL	1.2099 mL	2.4198 mL	6.0495 mL
	25 mM	0.1936 mL	0.9679 mL	1.9358 mL	4.8396 mL
	30 mM	0.1613 mL	0.8066 mL	1.6132 mL	4.0330 mL
	40 mM	0.1210 mL	0.6049 mL	1.2099 mL	3.0247 mL
	50 mM	0.0968 mL	0.4840 mL	0.9679 mL	2.4198 mL
	60 mM	0.0807 mL	0.4033 mL	0.8066 mL	2.0165 mL
	80 mM	0.0605 mL	0.3025 mL	0.6049 mL	1.5124 mL
	100 mM	0.0484 mL	0.2420 mL	0.4840 mL	1.2099 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Linsidomine16142-27-1SIN-1SIN1SIN 1Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Salutation

Applicant Name *

Email Address *

Phone Number *

Organization Name *

Department *

Requested quantity *

Country or Region *

Remarks