Conjugatable Lipids

DSPE-PEG2000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.

Cholesterol-PEG3-azide is a PEG derivative composed of Cholesterol, 3 PEG units and an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.

DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DSPE-PEG4000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG4000-Maleimide ammonium can be used in drug delivery research.

DSPE-PEG46-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DSPE-PEG46-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

DSPE-PEG36-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DSPE-PEG36-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.

PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity.

DSPE-succinic acid is a derivative of Succinic acid (HY-N0420) and an intermediate of DSPE-Doxorubicin. DSPE-succinic acid can be used to synthesize DSPE-Doxorubicin via EDC/NHS activation. DSPE-succinic acid is applicable to the research of triple-negative breast cancer.

DSPE-PEG2000-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications.

DSPE-PEG5000-endo-BCN is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG5000-endo-BCN can be used in drug delivery research.

16:0 propargyl SM (d18:1-16:0) is a clickable sphingolipid.

Sphingosine (d18:1) alkyne (compound 2b) is an alkyne-labeled Sphingosine (d18:1) that can be used in click chemistry reactions.

DSPE-PEG40000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles.

DSPE-PEG10000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles.

DSPE-PEG600-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG600-NHS is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG600-NHS can be used in the study of drug delivery.

DOPE-PEG5000-Mal is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Malcan be used in drug delivery research.

DOPE-PEG5000-Amine (DOPE-PEG5000-NH2) is a polyethylene glycol-derivatized phospholipid that can be used to construct liposomes and lipid nanoparticles. DOPE-PEG5000-Amine is used for non-covalent functionalization of single-walled carbon nanotubes (SWCNTs) to enhance their water dispersibility and biocompatibility. DOPE-PEG5000-Amine can be applied in research related to photothermal applications.

DOPE-PEG3400-Amine (DOPE-PEG3400-NH2) is a polyethylene glycol-derivatized phospholipid that can be used to construct liposomes and lipid nanoparticles. DOPE-PEG-Amine is used for non-covalent functionalization of single-walled carbon nanotubes (SWCNTs) to enhance their water dispersibility and biocompatibility. DOPE-PEG-Amine can be applied in research related to photothermal applications.

DOPE-PEG1000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG1000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.