Liproxstatin-1 (Standard)
Liproxstatin-1 (Standard) is the analytical standard of Liproxstatin-1 (HY-12726). This product is intended for research and analytical applications. Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM).
For research use only. We do not sell to patients.
- CAS No.: 950455-15-9
- Formula: C19H21ClN4
- Molecular Weight:340.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 950455-15-9
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Molecular Weight 340.85
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Formula C19H21ClN4
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SMILES
ClC1=CC(CNC2=NC3=CC=CC=C3NC24CCNCC4)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Friedmann Angeli JP, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 2014 Dec;16(12):1180-91. [Content Brief]
[2]. Zilka O, et al. On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death. ACS Cent Sci. 2017 Mar 22;3(3):232-243 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)