LSD1-IN-42
LSD1-IN-42 (Compound 7ae) is an orally active LSD1 inhibitor that potently inhibits LSD1 activity (IC50 = 0.08 μM). LSD1-IN-42 downregulates PD-L1 expression and enhances T cell-mediated tumor killing effects. LSD1-IN-42 demonstrates significant anti-gastric cancer activity by inhibiting tumor cell invasion and migration.
For research use only. We do not sell to patients.
- Formula: C22H20ClN3O7S
- Molecular Weight:505.93
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
LSD1 0.08 μM (IC50) |
Chemical Information
-
Molecular Weight 505.93
-
Formula C22H20ClN3O7S
-
SMILES
O=C1OCC(C1=C)C(O)C2=CN(C3=C2C=C(C=C3)Cl)S(=O)(C4=CC=C(C([N+]([O-])=O)=C4)N(C)C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)