1. Apoptosis
  2. c-Myc
  3. Lusianthridin

Lusianthridin 

Cat. No.: HY-121418
Handling Instructions

Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.

For research use only. We do not sell to patients.

Lusianthridin Chemical Structure

Lusianthridin Chemical Structure

CAS No. : 87530-30-1

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Description

Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling[1].

In Vitro

Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells[1].
Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively[1].

Cell Viability Assay[1]

Cell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells[1]. 0-100 μM.
Concentration: 0-100 μM.
Incubation Time: 24 h.
Result: Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells.
Molecular Weight

242.27

Formula

C₁₅H₁₄O₃

CAS No.

87530-30-1

SMILES

OC(C=C1CC2)=CC=C1C3=C2C=C(OC)C=C3O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Lusianthridinc-MycMycInhibitorinhibitorinhibit

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