LY-395153
LY-395153 is an AMPA receptor enhancer with the activity of binding to AMPA receptors. LY-395153 can bind to natural and recombinant AMPA receptors, and its binding is affected by AMPA receptor agonists and can be competitively or non-competitively inhibited by some compounds. It is a useful probe for marking unique regulatory sites of AMPA receptors.
For research use only. We do not sell to patients.
- CAS No.: 211313-51-8
- Formula: C19H24N2O3S
- Molecular Weight:360.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All iGluR Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.52 μM
Compound: 24
|
Inhibition of GluR4 expressed in HEK293 cells
Inhibition of GluR4 expressed in HEK293 cells
|
[PMID: 20839777] |
Chemical Information
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CAS No. 211313-51-8
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Molecular Weight 360.47
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Formula C19H24N2O3S
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SMILES
O=C(C1=CC=CC=C1)NC2=CC=C(C(CNS(=O)(C(C)C)=O)C)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)