Lysipressin (Standard)
Lysipressin (Standard) is the analytical standard of Lysipressin (HY-P0004). This product is intended for research and analytical applications. Lysipressin (Lysine vasopressin ; [Lys8]-Vasopressin ) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin stimulates contraction of rabbit bladder smooth muscle via V1-vasopressin receptor. The central hypotensive effect of Lysipressin depends on the sympathetic tone pathway. Lysipressin dose-dependently prolongs tail-flick latency in rats, producing a stable central antinociceptive effect. Lysipressin can be used in studies related to cardiovascular regulation, hypertension and pain.
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- CAS. Nr.: 50-57-7
- Formel: C46H65N13O12S2
- Molecular Weight:1056.22
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 50-57-7
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Molecular Weight 1056.22
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Formel C46H65N13O12S2
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SMILES
O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](N)CSSC1)=O)=O)([H])CC3=CC=CC=C3)=O)CCC(N)=O)=O)CC(N)=O)=O)N4[C@@H](CCC4)C(N[C@@H](CCCCN)C(NCC(N)=O)=O)=O
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Synonyms
Lysine vasopressin (Standard); [Lys8]-Vasopressin (Standard)
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Yu H, et al. Lysine Vasopressin-Induced Increases in Porcine Myometrial Contractility and Intracellular Ca²⁺ Concentrations of Myometrial Cells: Involvement of Oxytocin Receptors. Biology of Reproduction, 1995, 52: 584-590. [Content Brief]
[2]. Crankshaw D, et al. [Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle. European journal of pharmacology. 1989 Dec 07;173(2-3):183-8. [Content Brief]
[3]. Tran LD, et al. Effects of lysine-vasopressin and oxytocin on central cardiovascular control. British journal of pharmacology. 1982 Sep;77(1):69-73. [Content Brief]
[4]. Kordower JH, et al. Central antinociceptive effects of lysine-vasopressin and an analogue. Peptides. 1982;3(4):613-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Lysipressin (Standard) Related Classifications
HY-P0004R Related Classifications
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- Lysipressin (Standard)
- 50-57-7
- Lysine vasopressin (Standard)
- [Lys8]-Vasopressin (Standard)
- Reference Standards
- Endogenous Metabolite
- Oxytocin Receptor
- Vasopressin Receptor
- V1-vasopressin receptor
- porcine myometrial strips
- oxytocin (OT) receptor
- rabbit urinary bladder smooth muscle
- rat tail-flick latencies
- porcine myometrial membrane
- prepartum porcine myometrial cells
- porcine OT receptor
- male New Zealand white rabbit urinary bladder smooth muscle
- anesthetized dogs
- Inhibitor
- inhibitor
- inhibit