M700F048
Based on 1 Customer Validation
M700F048 is a major plant metabolite of fungicide Fluxapyroxad.
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 2056235-51-7
- Formula: C23H20F5N3O6
- Molecular Weight:529.41
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
M700F048 shows similar toxicity as the parent Fluxapyroxad[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2056235-51-7
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Appearance Solid
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Molecular Weight 529.41
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Formula C23H20F5N3O6
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Color White to off-white
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SMILES
O=C(C1=CN([C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)N=C1C(F)F)NC3=CC=CC=C3C4=CC(F)=C(F)C(F)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (188.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 2.5 mg/mL (4.72 mM); Clear solution; Need ultrasonic
This protocol yields a clear solution of 2.5 mg/mL.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (277 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Brancato A, et al. Modification of the existing maximum residue levels for fluxapyroxad in various crops. EFSA J. 2017 Sep 12;15(9):e04975. [Content Brief]
[2]. Hyun H Noh, et al. Dissipation, persistence, and risk assessment of fluxapyroxad and penthiopyrad residues in perilla leaf (Perilla frutescens var. japonica Hara). PLoS One. 2019 Apr 9;14(4):e0212209. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8889 mL | 9.4445 mL | 18.8890 mL | 47.2224 mL |
| 5 mM | 0.3778 mL | 1.8889 mL | 3.7778 mL | 9.4445 mL | |
| 10 mM | 0.1889 mL | 0.9444 mL | 1.8889 mL | 4.7222 mL | |
| 15 mM | 0.1259 mL | 0.6296 mL | 1.2593 mL | 3.1482 mL | |
| 20 mM | 0.0944 mL | 0.4722 mL | 0.9444 mL | 2.3611 mL | |
| 25 mM | 0.0756 mL | 0.3778 mL | 0.7556 mL | 1.8889 mL | |
| 30 mM | 0.0630 mL | 0.3148 mL | 0.6296 mL | 1.5741 mL | |
| 40 mM | 0.0472 mL | 0.2361 mL | 0.4722 mL | 1.1806 mL | |
| 50 mM | 0.0378 mL | 0.1889 mL | 0.3778 mL | 0.9444 mL | |
| 60 mM | 0.0315 mL | 0.1574 mL | 0.3148 mL | 0.7870 mL | |
| 80 mM | 0.0236 mL | 0.1181 mL | 0.2361 mL | 0.5903 mL | |
| 100 mM | 0.0189 mL | 0.0944 mL | 0.1889 mL | 0.4722 mL |
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