MAO-B-IN-25
Based on 1 Customer Validation
MAO-B-IN-25 (compound 92) is a selective MAO-B inhibitor with IC50s of 0.5 nM and 240 nM for MAO-A and MAO-B, respectively.
For research use only. We do not sell to patients.
- Purity: 99.11%
- CAS No.: 2097148-47-3
- Formula: C16H13BrO3
- Molecular Weight:333.18
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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MAO-B 0.5 nM (IC50) |
MAO-A 240 nM (IC50) |
Chemical Information
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CAS No. 2097148-47-3
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Appearance Solid
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Molecular Weight 333.18
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Formula C16H13BrO3
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Color White to pink
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SMILES
O=C1OC2=CC(OCC3=CC=C(C=C3)Br)=CC=C2CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (300.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0014 mL | 15.0069 mL | 30.0138 mL | 75.0345 mL |
| 5 mM | 0.6003 mL | 3.0014 mL | 6.0028 mL | 15.0069 mL | |
| 10 mM | 0.3001 mL | 1.5007 mL | 3.0014 mL | 7.5035 mL | |
| 15 mM | 0.2001 mL | 1.0005 mL | 2.0009 mL | 5.0023 mL | |
| 20 mM | 0.1501 mL | 0.7503 mL | 1.5007 mL | 3.7517 mL | |
| 25 mM | 0.1201 mL | 0.6003 mL | 1.2006 mL | 3.0014 mL | |
| 30 mM | 0.1000 mL | 0.5002 mL | 1.0005 mL | 2.5012 mL | |
| 40 mM | 0.0750 mL | 0.3752 mL | 0.7503 mL | 1.8759 mL | |
| 50 mM | 0.0600 mL | 0.3001 mL | 0.6003 mL | 1.5007 mL | |
| 60 mM | 0.0500 mL | 0.2501 mL | 0.5002 mL | 1.2506 mL | |
| 80 mM | 0.0375 mL | 0.1876 mL | 0.3752 mL | 0.9379 mL | |
| 100 mM | 0.0300 mL | 0.1501 mL | 0.3001 mL | 0.7503 mL |
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