MAO-B-IN-63
MAO-B-IN-63 (compound 4d) is a selective human monoamine oxidase-B (MAO-B) inhibitor with an IC50 of 0.581 μM. MAO-B-IN-63 blocks the catalytic cycle of monoamine oxidase, thereby reducing neurotransmitter metabolism and hydrogen peroxide production. MAO-B-IN-63 can be used in the research of Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 1898180-91-0
- Formula: C18H14N2O3
- Molecular Weight:306.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
MAO-B-IN-63 (Compound 4d) (3 nM-100 μM) inhibits recombinant human MAO-B with an IC50 of 0.581 μM; it inhibits MAO-A with an IC50 of 1.75 μM, and acts as a MAO-B-preferring inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1898180-91-0
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Molecular Weight 306.32
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Formula C18H14N2O3
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SMILES
O=C(NC1=O)C2=C1C=C(N(OC)C(C3=CC=C(C)C=C3)=C4)C4=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAO-B-IN-63 Related Classifications
HY-186308 Related Classifications
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