2. Anti-infection
  3. Enterovirus
  4. MDL-860

MDL-860 is a broad-spectrum antipicornavirus compound that has low cytotoxicity toward human cells. MDL-860 can be used for the research of virus infection.

For research use only. We do not sell to patients.

MDL-860

MDL-860 Chemical Structure

CAS No. : 78940-62-2

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Customer Review

Based on 1 publication(s) in Google Scholar

MDL-860 Related Antibodies

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Description

MDL-860 is a broad-spectrum antipicornavirus compound that has low cytotoxicity toward human cells. MDL-860 can be used for the research of virus infection[1].

Cellular Effect
Cell Line Type Value Description References
HEp-2 CC50
493 μM
Compound: MDL-860; DNB
Cytotoxicity against human Hep2 cells assessed as decrease in cell viability after 48 hrs by neutral red uptake assay
Cytotoxicity against human Hep2 cells assessed as decrease in cell viability after 48 hrs by neutral red uptake assay
[PMID: 28870395]
Vero EC50
5.84 μM
Compound: DPN
Effective concentration required to inhibit Coxsackie B3 virus induced cytopathicity in vero cells
Effective concentration required to inhibit Coxsackie B3 virus induced cytopathicity in vero cells
[PMID: 15658858]
Vero IC50
> 50 μM
Compound: 13; MDL860
Cytotoxicity against African green monkey Vero cells assessed by reduction in cell viability incubated for 72 hrs by resazurin dye fluorescence based assay
Cytotoxicity against African green monkey Vero cells assessed by reduction in cell viability incubated for 72 hrs by resazurin dye fluorescence based assay
[PMID: 34046598]
Molecular Weight

309.10

Formula

C13H6Cl2N2O3
CAS No.
SMILES

N#CC1=CC([N+]([O-])=O)=CC=C1OC2=CC=C(Cl)C(Cl)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MDL-860 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MDL-86078940-62-2MDL860MDL 860EnterovirusRhinovirusHRVHRVsHEVHEVsvirus infectionInhibitorinhibitorinhibit

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