MerTK-IN-2
MerTK-IN-2 (compound 15f) is an orally active MerTK inhibitor with an IC50 of 37.5 nM. MerTK-IN-2 can induce apoptosis. MerTK-IN-2 has antitumor activity with IC50 values of 1.79, 18.32, and 2.18 μM for human ovarian cancer cells A2780, breast cancer cells MDA-MB-231, and colon cancer cells HCT116, respectively.
For research use only. We do not sell to patients.
- Formula: C22H21FN6O
- Molecular Weight:404.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 404.44
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Formula C22H21FN6O
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SMILES
FC(C=C1)=CC=C1NC2=NC(NC3CCC(O)CC3)=C(C4=CC=CC(C#N)=N4)C=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MerTK-IN-2 Related Classifications
HY-174160 Related Classifications
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