Methylcobalamin-13C,d3
Based on 1 Customer Validation
Methylcobalamin-13C,d3 (Mecobalamin-13C,d3) is the 13C- and deuterium labeled Methylcobalamin (HY-B0586). Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.
For research use only. We do not sell to patients.
- Purity : 93.17%
- Formula: C6213CH88D3CoN13O14P
- Molecular Weight:1348.39
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 13422-55-4
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Appearance Solid
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Molecular Weight 1348.39
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Formula C6213CH88D3CoN13O14P
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Color Pink to red
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SMILES
C[C@]1([C@](C)2CC(N)=O)[N]([Co+3]([N](C([C@](C)3CC(N)=O)=C4C)=C5[C@H]3CCC(N)=O)([N](C(C(C)6C)=C5)=C([C@H]6CCC(N)=O)C(C)=C7[C@@]8(CCC(NC[C@H]9C)=O)C)([N](C%10=C%11)=CN([C@@H](O[C@@H]%12CO)[C@]([C@@H]%12O[P]([O-])(O9)=O)([H])O)C%10=CC(C)=C%11C)([13C-]([2H])([2H])[2H])[N-]7[C@]1([H])[C@@H]8CC(N)=O)=C4[C@H]2CCC(N)=O
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Synonyms
Mecobalamin-13C,d3; CH3-B12-13C,d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (74.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (261 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7416 mL | 3.7081 mL | 7.4163 mL | 18.5406 mL |
| 5 mM | 0.1483 mL | 0.7416 mL | 1.4833 mL | 3.7081 mL | |
| 10 mM | 0.0742 mL | 0.3708 mL | 0.7416 mL | 1.8541 mL | |
| 15 mM | 0.0494 mL | 0.2472 mL | 0.4944 mL | 1.2360 mL | |
| 20 mM | 0.0371 mL | 0.1854 mL | 0.3708 mL | 0.9270 mL | |
| 25 mM | 0.0297 mL | 0.1483 mL | 0.2967 mL | 0.7416 mL | |
| 30 mM | 0.0247 mL | 0.1236 mL | 0.2472 mL | 0.6180 mL | |
| 40 mM | 0.0185 mL | 0.0927 mL | 0.1854 mL | 0.4635 mL | |
| 50 mM | 0.0148 mL | 0.0742 mL | 0.1483 mL | 0.3708 mL | |
| 60 mM | 0.0124 mL | 0.0618 mL | 0.1236 mL | 0.3090 mL |