MINA53-IN-1
Based on 1 Customer Validation
MINA53-IN-1 is a selective MINA53 inhibitor with an IC50 of 1.5 μM. MINA53-IN-1 induces DNA damage, cell cycle arrest and apoptosis in tumor cells. MINA53-IN-1 can be used for cancer research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.55%
- CAS 番号: 2863676-85-9
- 分子式: C14H14N2O3S
- 分子量:290.34
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
14 μM
Compound: 10
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Antiproliferative activity against human HL-60 cells incubated for 48 hrs by WST-1 assay
Antiproliferative activity against human HL-60 cells incubated for 48 hrs by WST-1 assay
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[PMID: 34843649] |
体外実験
MINA53-IN-1 (compound 10) inhibits the proliferation of HL-60 acute promyelocytic leukemia cells after 48 h, with an IC50 of 14 μM[1].
MINA53-IN-1 (10-100 μM; 72-120 h) reduces the viability of U-87MG glioblastoma cells, MNK-45 gastric cancer cells and HeLa cervical cancer cells in a dose- and time-dependent manner[1].
MINA53-IN-1 (10-20 μM; 24 h) induces DNA damage, G2/M cell cycle arrest and apoptosis in U-87MG cells, and acts synergistically with Doxorubicin (HY-15142A) to enhance apoptosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:U-87MG malignant glioma cells, MNK-45 gastric carcinoma cells, HeLa cervical carcinoma cells
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Concentration:10, 50, 100 μM
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Incubation Time:72, 96, 120 h
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Result:Reduced cell viability in a dose- and time-dependent manner.
化学情報
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CAS 番号 2863676-85-9
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性状 Solid
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分子量 290.34
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分子式 C14H14N2O3S
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Color White to off-white
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SMILES
O=C(C1=CN=C(NC1=O)SCCCC2=CC=CC=C2)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
MINA53-IN-1 関連分類
HY-182436 関連分類
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