Mirabegron-d5
Mirabegron-d5 (YM178-d5) is deuterium labeled Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
For research use only. We do not sell to patients.
- CAS No.: 1258889-45-0
- Formula: C21H19D5N4O2S
- Molecular Weight:401.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1258889-45-0
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Unlabeled Cas 223673-61-8
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Molecular Weight 401.54
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Formula C21H19D5N4O2S
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SMILES
NC1=NC(CC(NC2=CC=C(C=C2)CCNC[C@@H](C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])O)=O)=CS1
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Synonyms
YM178-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Takasu T, et al. Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function. J Pharmacol Exp Ther. 2007 May;321(2):642-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mirabegron-d5 Related Classifications
HY-14773S3 Related Classifications
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