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Cat. No.: HY-162030

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MMT3-72

MMT3-72 is a weak inhibitor of JAK1. MMT3-72 has superior efficacy and reduced p-STAT3 in DSS-induced colitis.

For research use only. We do not sell to patients.

CAS No.: 2996158-39-3
Formula: C₄₀H₄₂N₈O₉S
Molecular Weight:810.87

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

MMT3-72 Chemical Structure

CAS No.: 2996158-39-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MMT3-72 is a weak inhibitor of JAK1. MMT3-72 has superior efficacy and reduced p-STAT3 in DSS-induced colitis^[1].

All JAK Isoforms :

Chemical Information

CAS No. 2996158-39-3
Molecular Weight 810.87
Formula C₄₀H₄₂N₈O₉S
SMILES

O=S(C1=CC=CC(NC2=NC(NC3=CC=C(OCCOC4=CC=C(/N=N/C5=CC=C(C(NCCC(O)=O)=O)C=C5)C=C4C(O)=O)C=C3)=NC=C2C)=C1)(NC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bu Y, et al. A gastrointestinal locally activating Janus kinase inhibitor to treat ulcerative colitis. J Biol Chem. 2023 Dec;299(12):105467. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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References

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MMT3-72

All JAK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MMT3-72 Related Classifications

HY-162030 Related Classifications