1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. MONIRO-1

MONIRO-1 

Cat. No.: HY-147638
Handling Instructions

MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively.

For research use only. We do not sell to patients.

MONIRO-1 Chemical Structure

MONIRO-1 Chemical Structure

CAS No. : 1909225-94-0

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Description

MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively[1].

IC50 & Target

Cav3.2

1.7 μM (IC50)

Cav3.1

3.3 μM (IC50)

Cav3.3

7.2 μM (IC50)

Cav2.2

34 μM (IC50)

Molecular Weight

458.91

Formula

C23H24ClFN4O3

CAS No.
SMILES

N/C(N)=N\CCCOC1=CC=C(C=C1)C(NC2=C(C=CC=C2)OC3=CC=C(C=C3)F)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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