2. Epigenetics Others
  3. Reference Standards Histone Methyltransferase
  4. MS049 (Standard)

MS049 (Standard) is the analytical standard of MS049 (HY-100360). This product is intended for research and analytical applications. MS049, a chemical probe, is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. MS049 reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 is not toxic and does not affect the growth of HEK293 cells.

For research use only. We do not sell to patients.

MS049 (Standard)

MS049 (Standard) Chemical Structure

CAS No. : 1502816-23-0

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Information

MS049 (Standard) is the analytical standard of MS049 (HY-100360). This product is intended for research and analytical applications. MS049, a chemical probe, is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. MS049 reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 is not toxic and does not affect the growth of HEK293 cells.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

248.36

Formula

C15H24N2O
CAS No.
SMILES

CNCCN1CCC(OCC2=CC=CC=C2)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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MS049 (Standard) Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MS049 (Standard)1502816-23-0Reference StandardsHistone MethyltransferaseepigeneticmodifiersselectiveargininedimethylationtoxicH4R3me2aHEK293cellsInhibitorinhibitorinhibit

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