1. Anti-infection
    Apoptosis
  2. Bacterial
    Thymidylate Synthase
  3. MtTMPK-IN-3

MtTMPK-IN-3 

Cat. No.: HY-144665
Handling Instructions

MtTMPK-IN-3 (compound 25) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 value of 0.12 μM. MtTMPK-IN-3 has inhibitory activity against Mtb H37Rv (MIC = 12.5 μM). MtTMPK-IN-3 exhibits certain cytotoxicity in human fibroblast cells MRC-5 (EC50 = 12.5 μM). MtTMPK-IN-3 can be used for researching tuberculosis.

For research use only. We do not sell to patients.

MtTMPK-IN-3 Chemical Structure

MtTMPK-IN-3 Chemical Structure

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Description

MtTMPK-IN-3 (compound 25) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 value of 0.12 μM. MtTMPK-IN-3 has inhibitory activity against Mtb H37Rv (MIC = 12.5 μM). MtTMPK-IN-3 exhibits certain cytotoxicity in human fibroblast cells MRC-5 (EC50 = 12.5 μM). MtTMPK-IN-3 can be used for researching tuberculosis[1].

IC50 & Target

IC50: 0.12 μM (MtbTMPK)[1]

Molecular Weight

460.35

Formula

C23H23Cl2N3O3

SMILES

CC1=CN(C(NC1=O)=O)C2CCN(CC2)CC3=CC(OC4=CC(Cl)=CC(Cl)=C4)=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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MtTMPK-IN-3
Cat. No.:
HY-144665
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