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Cat. No.: HY-W736861

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N-Phthaloylglutamic acid

N-Phthaloylglutamic acid is a partial agonist NMDA receptor with a K_i of 13 μM targeting Glu binding-site.

For research use only. We do not sell to patients.

CAS No.: 3227-01-8
Formula: C₁₃H₁₃NO₇
Molecular Weight:295.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

N-Phthaloylglutamic acid Chemical Structure

CAS No.: 3227-01-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

N-Phthaloylglutamic acid is a partial agonist NMDA receptor with a K_i of 13 μM targeting Glu binding-site^[1]^[2].

IC₅₀ & Target^[1]

NMDA Receptor

13 μM (Ki)

All iGluR Isoforms :

In Vitro

N-Phthaloylglutamic acid (Compound PhGA) shows a K_i of 13 μM for NMDA receptor^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3227-01-8
Molecular Weight 295.24
Formula C₁₃H₁₃NO₇
SMILES

OC(CC[C@@H](C(O)=O)NC(C1=C(C=CC=C1)C(O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Bonaccorso C, et al. Glutamate binding-site ligands of NMDA receptors. Curr Med Chem. 2011;18(36):5483-5506. [Content Brief]

[2]. Abd El-Wahab H, et al. Synthesis and characterisation of new modified anti-microbial polyesteramide resins by partial replacement the ingredient source of the polybasic acid based on tetrabromophthalic anhydride for organic surface coatings[J]. Egyptian Journal of Chemistry, 2015, 59(24): 1-15.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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N-Phthaloylglutamic acid

All iGluR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

N-Phthaloylglutamic acid Related Classifications

HY-W736861 Related Classifications