N2-MIE-dG TFA
N2-MIE-dG is the major DNA adduct formed after the activation of methyleugenol (ME) by SULT. N2-MIE-dG serves as a key biomarker for genotoxicity, metabolic activation, and potential carcinogenic risk.
For research use only. We do not sell to patients.
- Formula: C23H26F3N5O8
- Molecular Weight:557.48
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Under mutagenicity testing conditions, N2-MIE-dG is the predominant adduct formed in SULT-expressing *Salmonella typhimurium*[1].
N2-MIE-dG is abundantly formed in herring sperm DNA incubated with (±)-1'-acetoxymethyleugenol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 557.48
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Formula C23H26F3N5O8
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Color White to off-white
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SMILES
O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)NC(NC/C=C/C4=CC=C(OC)C(OC)=C4)=N1.O=C(O)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (179.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (281 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.7938 mL | 8.9689 mL | 17.9379 mL | 44.8447 mL |
| 5 mM | 0.3588 mL | 1.7938 mL | 3.5876 mL | 8.9689 mL | |
| 10 mM | 0.1794 mL | 0.8969 mL | 1.7938 mL | 4.4845 mL | |
| 15 mM | 0.1196 mL | 0.5979 mL | 1.1959 mL | 2.9896 mL | |
| 20 mM | 0.0897 mL | 0.4484 mL | 0.8969 mL | 2.2422 mL | |
| 25 mM | 0.0718 mL | 0.3588 mL | 0.7175 mL | 1.7938 mL | |
| 30 mM | 0.0598 mL | 0.2990 mL | 0.5979 mL | 1.4948 mL | |
| 40 mM | 0.0448 mL | 0.2242 mL | 0.4484 mL | 1.1211 mL | |
| 50 mM | 0.0359 mL | 0.1794 mL | 0.3588 mL | 0.8969 mL | |
| 60 mM | 0.0299 mL | 0.1495 mL | 0.2990 mL | 0.7474 mL | |
| 80 mM | 0.0224 mL | 0.1121 mL | 0.2242 mL | 0.5606 mL | |
| 100 mM | 0.0179 mL | 0.0897 mL | 0.1794 mL | 0.4484 mL |
N2-MIE-dG TFA Related Classifications
HY-185917 Related Classifications
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