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NAE-IN-3

NAE-IN-3 (compound 1) is a potent, selective and non-covalent competitive NEDD8-activating enzyme (NAE) inhibitor (IC50 = 0.8 μM). NAE-IN-3 inhibits NAE by blocking the ATP-binding domain. NAE-IN-3 exhibits selectivity over analogous E1 enzymes UAE and SAE. NAE-IN-3 can be used for cancer research.

For research use only. We do not sell to patients.

  • CAS No.: 951950-33-7
  • Formula: C17H18N4O6
  • Molecular Weight:374.35
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • NAE-IN-3 Chemical Structure
    NAE-IN-3 Chemical Structure
CAS No.: 951950-33-7
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  • NAE-IN-3 Chemical Structure
    NAE-IN-3 Chemical Structure
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  • NAE-IN-3