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Cat. No.: HY-135542R

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NBI-27914 (Standard)

NBI-27914 (Standard) is the analytical standard of NBI-27914 (HY-135542). This product is intended for research and analytical applications. NBI-27914 is a highly selective, high-affinity non-peptide competitive antagonist of human corticotropin-releasing factor receptor 1 (CRFR1). NBI-27914 primarily binds to the His199 and Met276 sites in the transmembrane domain of the receptor.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 184241-44-9
Formula: C₁₈H₂₀Cl₄N₄
Molecular Weight:434.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NBI-27914 (Standard) Chemical Structure

CAS No.: 184241-44-9

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Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 184241-44-9
Molecular Weight 434.19
Formula C₁₈H₂₀Cl₄N₄
SMILES

ClC1=C(NC2=C(Cl)C(N(CC3CC3)CCC)=NC(C)=N2)C(Cl)=CC(Cl)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Liaw CW, et al. Localization of agonist- and antagonist-binding domains of human corticotropin-releasing factor receptors. Mol Endocrinol. 1997;11(13):2048-2053. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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