NEK7-IN-2

NEK7-IN-2 is a NEK7 inhibitor. NEK7-IN-2 increases the thermal stability of NEK7, disrupts the NEK7-NLRP3 interaction, inhibits NLRP3 inflammasome assembly, and suppresses the release of IL-1β (with an IC50 of 0.048 μM against IL-1β). NEK7-IN-2 can be used for the research of inflammatory diseases.

For research use only. We do not sell to patients.

  • Formula: C27H28F4N6O2
  • Molecular Weight:544.54
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All NEKs Isoforms

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All NOD-like Receptor (NLR) Isoforms

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100 mg

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