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NF-κB-IN-11

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Based on 1 publication(s) in Google Scholar

NF-κB-IN-11 (Compound 3i) is a NF-κB inhibitor. NF-κB-IN-11 inhibits TNF-α induced activation of NF-κB pathway, and inhibits nuclear translocation of NF-κB. NF-κB-IN-11 down-regulates the expression levels of phosphor-IKK, IκBα, and NF-κB p65. NF-κB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-κB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay.

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  • Purity: 98.42%
  • CAS No.: 2768833-35-6
  • Formula: C19H18O5
  • Molecular Weight:326.34
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • NF-κB-IN-11 Chemical Structure
  • NF-κB-IN-11 Chemical Structure
    NF-κB-IN-11 Chemical Structure
CAS No.: 2768833-35-6
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