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Cat. No.: HY-170436

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NFh-NMe-2

NFh-NMe-2 is a photosensitizer, that interacts with nitroreductase, generates singlet oxygen in tumor cells, exhibits cytotoxicity in cancer cells, and induces apoptosis. NFh-NMe-2 exhibits antitumor efficacy in mouse models.

For research use only. We do not sell to patients.

Formula: C₃₂H₃₃IN₂O
Molecular Weight:588.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

NFh-NMe-2 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

Molecular Weight 588.52
Formula C₃₂H₃₃IN₂O
SMILES

CC1(C(/C=C/C(CCC2)=C3C2=CC4=C(O3)C=C(NC)C=C4)=[N+](C5=CC=C6C(C=CC=C6)=C51)CC)C.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhao C, et al., An Activatable Heavy-Atom-Free Upconversion Photosensitizer for Targeted Imaging and Treatment of Tumors. J Med Chem. 2024 Dec 26;67(24):22322-22331. [Content Brief]

Hot Topics

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Topics Photodynamic Therapy: Past, Current, Future
Photodynamic therapy (PDT) is a light-activated therapeutic modality that combines photosensitizers, oxygen, and specific light wavelengths to generate reactive oxygen species for selective cellular destruction.

2026-06-02

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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