NLRP3-IN-70
NLRP3-IN-70 (Compound 5m) is an NLRP3 inflammasome inhibitor with low oral bioavailability. NLRP3-IN-70 can directly bind to the NACHT domain of the NLRP3 protein and block the interaction of NLRP3 and ASC, thus inhibiting ASC oligomerization and NLRP3 inflammasome assembly. NLRP3-IN-70 can be used in the research of sepsis and nonalcoholic steatohepatitis.
For research use only. We do not sell to patients.
- CAS No.: 1997362-01-2
- Formula: C23H23NO5
- Molecular Weight:393.43
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
NLRP3 1.34 μM (Kd) |
Chemical Information
-
CAS No. 1997362-01-2
-
Molecular Weight 393.43
-
Formula C23H23NO5
-
SMILES
O=C(C1=C(C2=C3C4=C(C(C)(CCC4)C)C=C2)OC=C1C(N5CCOCC5)=O)C3=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NLRP3-IN-70 Related Classifications
HY-172134 Related Classifications
Powered by Bioz