Nortadalafil (Standard)
Nortadalafil (Standard) is the analytical standard of Nortadalafil. This product is intended for research and analytical applications. Nortadalafil , a new tadalafil (HY-90009A) analogue detected in health foods, is a PDE5 inhibitor. Nortadalafil is used in the research of erectile dysfunction (ED). Nortadalafil can be formed by closing the diketopiperazine ring in high yield. Nortadalafil is promising for research of pulmonary arterial hypertension[4].
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 171596-36-4
- Formula: C21H17N3O4
- Molecular Weight:375.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 171596-36-4
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Molecular Weight 375.38
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Formula C21H17N3O4
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SMILES
O=C1NCC(N([C@@H]1C2)[C@H](C3=CC=C(OCO4)C4=C3)C5=C2C6=C(N5)C=CC=C6)=O
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Synonyms
Demethyl Tadalafil (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Daugan, et al. The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogue. Journal of Medicinal Chemistry (2003), 46(21), 4533-4542. [Content Brief]
[2]. Porst H, et al. Chronic PDE-5 inhibition in patients with erectile dysfunction - a treatment approach using tadalafil once-daily. Expert Opin Pharmacother. 2012 Jul;13(10):1481-94. [Content Brief]
[3]. Frey MK, Lang I. Tadalafil for the treatment of pulmonary arterial hypertension. Expert Opin Pharmacother. 2012 Apr;13(5):747-55. [Content Brief]
[5]. Fukiwake T, et al. [The Configuration of Tadalafil and Tadalafil Analogues Found in Dietary Supplements][J]. Shokuhin Eiseigaku Zasshi. 2021;62(2):65-72. [Content Brief]
[6]. Beghyn T, et al. PDE5 inhibitors: An original access to novel potent arylated analogues of tadalafil. Bioorg Med Chem Lett[J]. 2007 Feb 1;17(3):789-92. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)