1. Immunology/Inflammation
  2. NO Synthase
  3. NOS1-IN-1

NOS1-IN-1 

Cat. No.: HY-130452
Handling Instructions

NOS1-IN-1 is a selective and cell-permeable nNOS inhibitor with a Ki of 120 nM. NOS1-IN-1 exhibits 2617-fold and 325-fold selectivity over eNOS (Ki=39 μM) and iNOS (Ki=325 μM) , respectively. NOS1-IN-1 can be used for the research of neurological disease, including cerebral palsy (CP).

For research use only. We do not sell to patients.

NOS1-IN-1 Chemical Structure

NOS1-IN-1 Chemical Structure

CAS No. : 357965-99-2

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Description

NOS1-IN-1 is a selective and cell-permeable nNOS inhibitor with a Ki of 120 nM. NOS1-IN-1 exhibits 2617-fold and 325-fold selectivity over eNOS (Ki=39 μM) and iNOS (Ki=325 μM) , respectively[1]. NOS1-IN-1 can be used for the research of neurological disease, including cerebral palsy (CP)[2].

IC50 & Target

Ki: 120 nM (nNOS)[1]

Molecular Weight

589.37

Formula

C₁₄H₂₄F₉N₇O₈

CAS No.

357965-99-2

SMILES

N=C(N[N+]([O-])=O)NCCC[[email protected]](N)CNCCN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

NOS1-IN-1NO SynthaseNitric oxide synthasesNOSNeurological disease,?cerebral palsyCPneuronalInhibitorinhibitorinhibit

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NOS1-IN-1
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