NPD7155
NPD7155 is a purine-based competitive inhibitor of MTH1, designed to target cancer cells while exhibiting off-target effects that contribute to its cytotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 924764-38-5
- Formula: C15H21N5
- Molecular Weight:271.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
100 nM
Compound: NPD7155
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Inhibition of DsRed-fused MTH1 (unknown origin) expressed in HEK293T cells using 8-oxo-dGTP as substrate
Inhibition of DsRed-fused MTH1 (unknown origin) expressed in HEK293T cells using 8-oxo-dGTP as substrate
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[PMID: 28280261] |
Chemical Information
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CAS No. 924764-38-5
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Molecular Weight 271.36
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Formula C15H21N5
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SMILES
CC1(CC2CC(C)(C1)C)CN2C3=NC=NC4=C3NC=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)