2. JAK/STAT Signaling Others Protein Tyrosine Kinase/RTK Epigenetics
  3. EGFR Reference Standards Histone Acetyltransferase Epigenetic Reader Domain
  4. NSC 228155 (Standard)

NSC 228155 (Standard) is the analytical standard of NSC 228155 (HY-101084). This product is intended for research and analytical applications. NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR. NSC 228155 is also a potent inhibitor of KIX-KID interaction, inhibits kinase-inducible domain (KID) from CREB and KID-interacting domain (KIX) from CBP, with an IC50 of 0.36 μM.

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NSC 228155 (Standard)

NSC 228155 (Standard) Chemical Structure

CAS No. : 113104-25-9

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Information

NSC 228155 (Standard) is the analytical standard of NSC 228155 (HY-101084). This product is intended for research and analytical applications. NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR. NSC 228155 is also a potent inhibitor of KIX-KID interaction, inhibits kinase-inducible domain (KID) from CREB and KID-interacting domain (KIX) from CBP, with an IC50 of 0.36 μM.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

290.25

Formula

C11H6N4O4S
CAS No.
SMILES

[O-][N+]1=CC=CC=C1SC2=CC=C([N+]([O-])=O)C3=NON=C32
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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NSC 228155 (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSC 228155 (Standard)113104-25-9EGFRReference StandardsHistone AcetyltransferaseEpigenetic Reader DomainEpidermal growth factor receptorErbB-1HER1HATsHATInhibitorinhibitorinhibit

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HY-101084R
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