NSC 620023 TFA
NSC 620023 TFA is a highly selective butyrylcholinesterase (BChE) inhibitor with an IC50 of 32 nM. NSC 620023 TFA acts via π-stacking interactions with dual benzimidazole moieties and hydrophobic interactions within the BChE binding site. NSC 620023 TFA can be used for the research of alzheimer’s disease.
For research use only. We do not sell to patients.
- Formula: C31H30F6N4O5S2
- Molecular Weight:716.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hBCHE 32 nM (IC50) |
hAChE >>5000 nM (IC50) |
NSC 620023 (5 μM; 10-30 min) TFA potently and selectively inhibits purified human butyrylcholinesterase with an IC50 of 32 nM and shows no inhibition of acetylcholinesterase at concentrations up to 5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 716.71
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Formula C31H30F6N4O5S2
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SMILES
OC1=C(C=C(C=C1CSCCC2=NC3=C(C=CC=C3)N2)C)CSCCC4=NC5=C(N4)C=CC=C5.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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