NST-628 (Standard)

NST-628 (Standard) is the analytical standard of NST-628 (HY-158115). This product is intended for research and analytical applications. NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors.

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  • CAS No.: 3002056-30-3
  • 화학식: C22H18F2N4O5S
  • 분자량:488.46
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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