NUCC-0200808
NUCC-0200808 (Compound 12g) is an inhibitor of MNK1 with an IC50 of 42 nM. NUCC-0200808 reduces eIF4E phosphorylation and cell viability in AML cells, and induces apoptosis. NUCC-0200808 holds promise for research in the field of leukemia.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C15H14ClN5O
- Peso molecular:315.76
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
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MNK1 |
MNK2 |
Chemical Information
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Peso molecular 315.76
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Fòrmula C15H14ClN5O
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SMILES
ClC1=CN=C(N2C=NC3=C2C=CC=C3)N=C1OC4CCNC4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)