ONCOII
ONCOII is an Mps1 inhibitor with an IC50 of 10.8 nM. The inhibitory activity of ONCOII against Mps1 is affected by naturally occurring mutations in the Mps1 gene, and cells with Mps1 mutations exhibit increased resistance to ONCOII. ONCOII can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1263564-94-8
- Formula: C24H25N7O
- Molecular Weight:427.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 1263564-94-8
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Molecular Weight 427.50
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Formula C24H25N7O
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SMILES
N#CC1=CC=C(NC2=CC(OCC#N)=C(C3=CN(C)N=C3)C=C2)N=C1NC4CCCCC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)