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Cat. No.: HY-169959

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OTs-PEG3-NHCO-Thalidomide

OTs-PEG3-NHCO-Thalidomide is a ubiquitin E3 ligase and linker for PROTAC α-synuclein degrader 6 (HY-157839), which can be used in research on neurodegenerative diseases.

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CAS No.: 2716123-18-9
Formule: C₃₀H₃₅N₃O₁₂S
Masse moléculaire:661.68

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

OTs-PEG3-NHCO-Thalidomide Chemical Structure

CAS No.: 2716123-18-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

OTs-PEG3-NHCO-Thalidomide is a ubiquitin E3 ligase and linker for PROTAC α-synuclein degrader 6 (HY-157839), which can be used in research on neurodegenerative diseases^[1].

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Chemical Information

CAS No. 2716123-18-9
Masse moléculaire 661.68
Formule C₃₀H₃₅N₃O₁₂S
SMILES

O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(OCC(NCCOCCOCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)=O)=C3C1=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wentao Zhu, et al. Discovery of Effective Dual PROTAC Degraders for Neurodegenerative Disease-Associated Aggregates. J Med Chem. 2024 Mar 14;67(5):3448-3466. [Content Brief]

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Calculateur de molarité

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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OTs-PEG3-NHCO-Thalidomide

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

OTs-PEG3-NHCO-Thalidomide Related Classifications

HY-169959 Related Classifications

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