Ovalbumin (154-159)

Cat. No.: HY-P4279 Purity: 99.94%: Data Sheet
COA

SDS
Handling Instructions
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Ovalbumin (154-159) is a protein fragment consisting of residues 154-159 of chicken ovalbumin. Ovalbumin (154-159) is also a poorly conserved sequence (Thr-Asn-Gly-Ile-Ile-Arg) in the α-subunit of the Torpedo acetylcholine receptor, located within the α150-164 epitope region, and exhibits significant angiotensin-converting enzyme (ACE) inhibitory activity.

For research use only. We do not sell to patients.

Ovalbumin (154-159) Chemical Structure

CAS No. : 1370698-94-4

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Purity & Documentation
References
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Description

IC₅₀ & Target

electric eel AChE

In Vivo

Although Ovalbumin (154-159) exhibits ACE inhibitory activity, its antihypertensive potential cannot be guaranteed. Therefore, it is necessary to verify the antihypertensive effect of this type of ACE inhibitory peptide in spontaneously hypertensive rats (SHRs)^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

672.77

Formula

C₂₈H₅₂N₁₀O₉

CAS No.

1370698-94-4

Appearance

Solid

Color

White to off-white

Sequence

Thr-Asn-Gly-Ile-Ile-Arg

Sequence Shortening

TNGIIR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 10 mg/mL (14.86 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4864 mL	7.4320 mL	14.8639 mL
5 mM	0.2973 mL	1.4864 mL	2.9728 mL
10 mM	0.1486 mL	0.7432 mL	1.4864 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.94%

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Data Sheet (274 KB) SDS (252 KB)

COA (247 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Das MK, et al. Epitope mapping of antibodies to acetylcholine receptor alpha subunits using peptides synthesized on polypropylene pegs. Biochemistry. 1991;30(9):2470-2477. [Content Brief]

[2]. Anami Y, et al. Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular Dynamics. J Med Chem. 2016;59(17):7888-7900. [Content Brief]

[3]. Gluschankof P, et al. A C-terminal domain conserved in precursor processing proteases is required for intramolecular N-terminal maturation of pro-Kex2 protease. EMBO J. 1994;13(10):2280-2288. [Content Brief]

[4]. Zhi PY, et, al. Interaction mechanism of egg white- derived ACE inhibitory peptide TNGIIR with ACE and its effect on the expression of ACE and AT1 receptor. Food Science and Human Wellness. 2020,9(1):52-7.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.4864 mL	7.4320 mL	14.8639 mL	37.1598 mL
	5 mM	0.2973 mL	1.4864 mL	2.9728 mL	7.4320 mL
	10 mM	0.1486 mL	0.7432 mL	1.4864 mL	3.7160 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.