2. GPCR/G Protein Neuronal Signaling
  3. Orexin Receptor (OX Receptor)
  4. OX2R-IN-2

OX2R-IN-2 (compound 63c) is an agonist for orexin receptor type 2 (OX2R) with EC50 of 339 nM. OX2R-IN-2 is able to cross the blood-brain barrier and exhibits no cytotoxicity in cells

For research use only. We do not sell to patients.

OX2R-IN-2 Chemical Structure

OX2R-IN-2 Chemical Structure

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OX2R-IN-2 Related Antibodies

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Description

OX2R-IN-2 (compound 63c) is an agonist for orexin receptor type 2 (OX2R) with EC50 of 339 nM. OX2R-IN-2 is able to cross the blood-brain barrier and exhibits no cytotoxicity in cells[1]

IC50 & Target

OX2 Receptor

339 nM (EC50)

Molecular Weight

458.60

Formula

C28H34N4O2
SMILES

CC(C=C1)=CC=C1C[C@@H](COCCOC)N2C3=NC=CC=C3N(C(C)C4=CC=C(C)C=C4)C2=N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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OX2R-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OX2R-IN-2Orexin Receptor (OX Receptor)Hypocretin ReceptorHCRT ReceptorNarcolepsyOXBHEK293Gq signalingorexin receptorInhibitorinhibitorinhibit

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