1. Membrane Transporter/Ion Channel
  2. P-glycoprotein
  3. P-gp modulator 2

P-gp modulator 2 

Cat. No.: HY-146117
Handling Instructions

P-gp modulator 2 (Compound 27) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator.

For research use only. We do not sell to patients.

P-gp modulator 2 Chemical Structure

P-gp modulator 2 Chemical Structure

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Description

P-gp modulator 2 (Compound 27) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator[1].

In Vitro

P-gp modulator 2 (Compound 27) shows cytotoxicity on L5178Y parental (L5178Y-PAR) and human ABCB1-gene transfected (L5178Y-MDR) mouse T-lymphoma cells with IC50 values of 8.0 ± 1.1 and 10.7 ± 1.1 µM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

470.32

Formula

C22H20BrN3O4

SMILES

COC1=CC=C(C=C1)[[email protected]@H]2C/C(C3=C(O2)C=C(C=C3O)OC)=N\NC4=CC=C(C=N4)Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
P-gp modulator 2
Cat. No.:
HY-146117
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