2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Pacmilimab

Pacmilimab  (Synonyms: CX-072)

Cat. No.: HY-P99799 Purity: 95.00%
COA

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Pacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity.

For research use only. We do not sell to patients.

Pacmilimab Chemical Structure

Pacmilimab Chemical Structure

CAS No. : 2145091-51-4

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Description

Pacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity[1].

In Vivo

Pacmilimab induces antitumor responses comparable to those of the same dose of the parental antibody in mice bearing MC38 tumors[1].
Pacmilimab accumulates in murine PD-L1-expressing tumors with minimal uptake in peripheral, non-cancerous lymphoid tissue, consistent with limited uptake in non-tumor PD-L1-expressing tissues and protection against autoimmunity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Pacmilimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.00%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Pacmilimab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pacmilimab2145091-51-4CX-072CX072CX 072PD-1/PD-L1PD-1/Programmed death-ligand 1Inhibitorinhibitorinhibit

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