PAD2/4-IN-1
PAD2/4-IN-1 (Compound 4f) is an orally active inhibitor of PAD2 and PAD4 with IC50 values of 23 nM and 10 nM, respectively. PAD2/4-IN-1 can inhibit protein citrullination in neutrophils and reduce hERG channel liabilities. PAD2/4-IN-1 can be used in the research of autoimmune diseases, neurological disorders, and cancers.
For research use only. We do not sell to patients.
- Formula: C26H27Cl2N7O
- Molecular Weight:524.44
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
Molecular Weight 524.44
-
Formula C26H27Cl2N7O
-
SMILES
O=C(NC)[C@@H](N)C1CCN(C2=NC=CC3=C2C=CC=C3C4=NC(C5=NN(C)C=C5)=C(Cl)C=C4Cl)CC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)